Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218365 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2NLRP3NR1H4ALDH1A1LMNA | |
| SCHEMBL7225109 | 0.88 | NPSR1 (0.49) | SMN1; SMN2NLRP3ALDH1A1KDM4ELMNA | |
| SCHEMBL7223600 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2APDK2NLRP3NR1H4 | |
| SCHEMBL7224057 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2NLRP3NR1H4ALDH1A1KDM4E | |
| SCHEMBL7224215 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2ANLRP3MEN1ALDH1A1 | |
| SCHEMBL11422549 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5941054 | 0.80 | NLRP3 (0.56) | SMN1; SMN2KMT2ANLRP3MEN1ALDH1A1 | |
| SCHEMBL7224731 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2PDK1PDK2PDK3PDK4 | |
| SCHEMBL30502814 | 0.80 | NLRP3 (0.56) | SMN1; SMN2KMT2ANLRP3MEN1ALDH1A1 | |
| SCHEMBL7217431 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2ANLRP3MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |