Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064071 | 0.87 | LMNA (0.58) | LMNACYP3A4ABCB11CYP1A2ADRA2A | |
| SCHEMBL5061285 | 0.85 | LMNA (0.51) | LMNACYP3A4ABCB11CYP1A2ADRA2A | |
| SCHEMBL5055883 | 0.84 | CYP3A4 (0.56) | LMNACYP3A4ABCB11CYP1A2ADRA2A | |
| SCHEMBL5064345 | 0.84 | LMNA (0.52) | LMNACYP3A4ABCB11CYP1A2ADRA2A | |
| SCHEMBL5066113 | 0.84 | CCR1 (0.57) | LMNACYP3A4ABCB11CYP1A2ADRA2A | |
| SCHEMBL5063890 | 0.84 | FAAH (0.56) | LMNACYP3A4ABCB11CYP1A2ADRA2A | |
| SCHEMBL5065927 | 0.84 | LMNA (0.58) | LMNACYP3A4ABCB11CYP1A2ADRA2A | |
| SCHEMBL5064470 | 0.83 | KDM4E (0.57) | LMNACYP3A4ABCB11CYP1A2ADRA2A | |
| SCHEMBL5060679 | 0.83 | CYP3A4 (0.54) | LMNACYP3A4ABCB11CYP1A2ADRA2A | |
| SCHEMBL5059937 | 0.83 | LMNA (0.55) | LMNACYP3A4ABCB11CYP1A2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573266-B1 | Compounds used for treating multitiple sclerosis and encephalomyelitis | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-06-03 | — | — | US | disclosed |