Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.46 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.46 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.46 |
| ▸ | CBFB | Q13951 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14582960 | 0.89 | ALDH1A1 (0.49) | ALDH1A1TDP1GAAL3MBTL1HTT | |
| SCHEMBL5498884 | 0.86 | ALDH1A1 (0.46) | ALDH1A1TDP1GAAL3MBTL1HTT | |
| SCHEMBL7217379 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TDP1GAAHTTSMN1; SMN2 | |
| SCHEMBL10227598 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TDP1GAAL3MBTL1HTT | |
| SCHEMBL7224039 | 0.81 | KDM4E (0.54) | ALDH1A1TDP1GAAHTTMEN1 | |
| SCHEMBL519374 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TDP1GAAHTTSMN1; SMN2 | |
| SCHEMBL17378848 | 0.81 | GAA (0.46) | ALDH1A1TDP1GAAL3MBTL1HTT | |
| SCHEMBL5496486 | 0.81 | CASP3 (0.43) | ALDH1A1TDP1GAASMN1; SMN2RECQL | |
| SCHEMBL5492615 | 0.79 | RECQL (0.44) | ALDH1A1TDP1GAAHTTSMN1; SMN2 | |
| SCHEMBL11879883 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TDP1GAAL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |