Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 12/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.40 |
| ▸ | DRD4 | P21917 | 7/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212047 | 0.84 | ADRA1A (0.60) | ADRA1AADRA1DADRA1B | |
| SCHEMBL6962974 | 0.75 | ADRA1A (0.50) | ADRA1AADRA1DADRA1BDRD4DRD2 | |
| SCHEMBL7962310 | 0.74 | ADRA1A (0.58) | ADRA1AADRA1DADRA1B | |
| SCHEMBL8134486 | 0.72 | ADRA1A (0.65) | ADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL7959697 | 0.71 | ADRA1A (0.65) | ADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL7966238 | 0.71 | ADRA1A (0.63) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7966205 | 0.71 | ADRA1A (0.63) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7218041 | 0.71 | ADRA1A (0.61) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7966207 | 0.71 | ADRA1A (0.63) | ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL7965667 | 0.70 | ADRA1A (0.62) | ADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620815-B1 | Selective antagonists for human alpha 1A receptors; benign prostatic hyperplasia, impotency, cardiac arrhythmia treatment; anticholesterol agents; intraocular pressure reduction | SYNAPTIC PHARMACEUTICAL CORPORATION | 2003-09-16 | — | — | US | disclosed |