Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27555651 | 0.82 | CTBP2 (0.38) | KMT2AHTTGAASMN1; SMN2LMNA | |
| SCHEMBL6451970 | 0.77 | GAA (0.50) | KMT2AHTTGAASMN1; SMN2LMNA | |
| Water SCHEMBL17802313 | 0.76 | GAA (0.48) | KMT2AHTTGAASMN1; SMN2LMNA | |
| SCHEMBL509869 | 0.75 | ALDH1A1 (0.53) | KMT2AHTTGAALMNAALDH1A1 | |
| SCHEMBL3222142 | 0.75 | TDP1 (0.58) | KMT2AHTTSMN1; SMN2POLBMAPT | |
| SCHEMBL4677316 | 0.75 | HTT (0.44) | KMT2AHTTGAALMNANPSR1 | |
| SCHEMBL14149819 | 0.74 | NPC1 (0.37) | SMN1; SMN2POLBMAPTCNR2GPR55 | |
| SCHEMBL4673722 | 0.74 | LMNA (0.40) | KMT2ASMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL3218824 | 0.73 | HTT (0.43) | HTTGAALMNANPSR1POLB | |
| SCHEMBL3221601 | 0.73 | HTT (0.47) | KMT2AHTTGAALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620841-B1 | Furan or benzofuran derivatives substituted with triazole; acquired immunodeficiency syndrome (AIDS) | SHIONOGI & CO., LTD. (JP) | 2003-09-16 | — | — | US | disclosed |