Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219386 | 0.79 | MAPT (0.46) | MAOB | |
| SCHEMBL14451036 | 0.72 | PDGFRB (0.53) | PDGFRBPDGFRACYP2A6ALOX5 | |
| SCHEMBL7223514 | 0.71 | MAOA (0.41) | MAOA | |
| SCHEMBL18724350 | 0.69 | ALDH1A1 (0.41) | ADORA2AMAOBMAOA | |
| SCHEMBL16485457 | 0.69 | ALDH1A1 (0.37) | MAOAESR1ESR2 | |
| SCHEMBL8476247 | 0.68 | CSNK2A2 (0.46) | MAOB | |
| SCHEMBL13002777 | 0.68 | ALDH1A1 (0.43) | ADORA2AMAOBMAOA | |
| SCHEMBL1721865 | 0.66 | MAPT (0.38) | S1PR4 | |
| SCHEMBL3176584 | 0.66 | MAOA (0.41) | MAOBMAOACYP2A6 | |
| SCHEMBL17131520 | 0.64 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576771-B1 | Pesticides, herbicides and fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-10 | — | — | US | disclosed |
| EP-0865438-B1 | OXYMETHOXY-3-ARYL-PYRONE DERIVATIVES | BAYER AG (DE) | 2001-10-17 | — | — | EP | disclosed |
| US-6071937-A | PESTICIDES, FUNGICIDES, INSECTICIDES, HERBICIDES, MITICIDES, PARASITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-06 | — | — | US | disclosed |
| EP-0865438-A1 | OXYMETHOXY-3-ARYL-PYRONE DERIVATIVES | BAYER AG (DE) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997019941-A1 | OXYMETHOXY-3-ARYL-PYRONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-05 | — | — | WO | disclosed |