Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27869644 | 0.82 | NPC1 (0.54) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL28891976 | 0.81 | CYP1A2 (0.46) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL5750011 | 0.81 | CYP1A2 (0.46) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL28411636 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| Formaldehyde SCHEMBL28892043 | 0.78 | NPC1 (0.54) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL2521104 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL9764099 | 0.77 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL29070912 | 0.77 | ERN1 (0.50) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL10435169 | 0.77 | TDP1 (0.45) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL31162741 | 0.77 | ALDH1A1 (0.68) | ALDH1A1HPGDHSD17B10CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171587-A1 | Antimicrobial 2-pyridones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2003-09-11 | — | — | US | disclosed |
| US-6509349-B1 | suppressing the growth or reproduction of microorganisms, such as bacteria. For example, such antibacterials and other antimicrobials are described in Antibiotics, Chemotherapeutics, and Antibacterial Agents for Disease | THE PROCTER & GAMBLE COMPANY | 2003-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171587-A1 | Antimicrobial 2-pyridones, their compositions and uses | PIR, PRDX6, CLPP | ALDH1A1 3730/4885HPGD 1591/4885HSD17B10 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.