Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.61 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9454035 | 0.85 | CYP4F2 (0.58) | CYP4F2CYP4A11MEP1BRAB9ANPC1 | |
| SCHEMBL915149 | 0.84 | LOXL2 (0.64) | CYP4F2CYP4A11RAB9AMAPTALDH1A1 | |
| SCHEMBL129801 | 0.84 | CYP4F2 (0.71) | CYP4F2CYP4A11MEP1BRAB9ANPC1 | |
| SCHEMBL6147651 | 0.81 | CA1 (0.58) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2089661 | 0.81 | CYP4F2 (0.68) | CYP4F2CYP4A11MEP1BRAB9ANPC1 | |
| SCHEMBL128387 | 0.81 | CYP4F2 (0.72) | CYP4F2CYP4A11MEP1BRAB9ANPC1 | |
| SCHEMBL110276 | 0.80 | CYP4F2 (0.65) | CYP4F2CYP4A11RAB9ANPC1ALDH1A1 | |
| SCHEMBL129800 | 0.80 | CYP4F2 (0.66) | CYP4F2CYP4A11MEP1BRAB9ANPC1 | |
| SCHEMBL2450193 | 0.80 | LOXL2 (0.71) | CYP4F2CYP4A11MEP1BRAB9ANPC1 | |
| SCHEMBL12035616 | 0.80 | CYP4F2 (0.75) | CYP4F2CYP4A11MEP1BRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624188-B1 | Administered to treat or prevent one or more of the diseases and conditions selected from the group consisting of dermatoses, atherosclerosis and restenosis resulting from neointimal hyperproliferation, non-malignant and | ALLERGAN, INC. | 2003-09-23 | — | — | US | disclosed |
| US-5556996-A | Oxiranyls disubstituted with a phenyl group and a substituted chromanyl or tetrahydroquinolinyl group having retinoid like activity | ALLERGAN (US) | 1996-09-17 | — | — | US | disclosed |
| EP-0626940-A1 | SUBSTITUTED PHENYLETHENYL COMPOUNDS HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN, INC. (US) | 1994-12-07 | — | — | EP | disclosed |
| US-5326898-A | Substituted phenylethenyl compounds having retinoid-like biological activity | ALLERGAN, INC. (US) | 1994-07-05 | — | — | US | disclosed |
| US-5324840-A | Skin disorders | ALLERGAN, INC. (US) | 1994-06-28 | — | — | US | disclosed |
| WO-1993016029-A1 | SUBSTITUTED PHENYLETHENYL COMPOUNDS HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN, INC. (US) | 1993-08-19 | — | — | WO | disclosed |