Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31601979 | 0.86 | PDIA6 (0.40) | DUTALDH1A1GAAPDIA6 | |
| SCHEMBL7703049 | 0.84 | DUT (0.36) | DUT | |
| SCHEMBL5718625 | 0.82 | GAA (0.39) | ALDH1A1GAAHSD17B10 | |
| SCHEMBL29975298 | 0.82 | GAA (0.39) | ALDH1A1GAAHSD17B10 | |
| SCHEMBL1127903 | 0.81 | MAPT (0.40) | ALDH1A1GAAHSD17B10PDIA6 | |
| SCHEMBL5718608 | 0.81 | GAA (0.38) | ALDH1A1GAAHSD17B10 | |
| SCHEMBL8086471 | 0.81 | GAA (0.38) | ALDH1A1GAAHSD17B10 | |
| SCHEMBL8084876 | 0.81 | GAA (0.38) | ALDH1A1GAAHSD17B10 | |
| SCHEMBL8072193 | 0.81 | GAA (0.38) | ALDH1A1GAAHSD17B10 | |
| SCHEMBL5718660 | 0.81 | GAA (0.38) | ALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37979-E1 | Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof | MITSUBISHI CHEMICAL CORPORATION | 2003-02-04 | — | — | US | disclosed |
| EP-0829476-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5461060-A | Antiretroviral activity | MITSUBISHI KASEI CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |