Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20508981 | 0.91 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP3A4HIF1ACASP1 | |
| SCHEMBL10043791 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CYP3A4HIF1ACASP1 | |
| SCHEMBL31670654 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CYP3A4HIF1ACASP1 | |
| SCHEMBL27520843 | 0.83 | MEN1 (0.56) | ALDH1A1HSD17B10CYP3A4TDP1PRKCZ | |
| SCHEMBL28346139 | 0.80 | MEN1 (0.50) | ALDH1A1HSD17B10TDP1CYP1B1PRKCZ | |
| SCHEMBL2153752 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP3A4HIF1ACASP1 | |
| SCHEMBL29487594 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP3A4HIF1ACASP1 | |
| SCHEMBL23045955 | 0.79 | MEN1 (0.51) | ALDH1A1HSD17B10TDP1ALOX15CYP1B1 | |
| SCHEMBL5250994 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CYP3A4HIF1ACASP1 | |
| SCHEMBL688181 | 0.76 | NQO2 (0.61) | ALDH1A1HSD17B10CYP3A4HIF1ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6582837-B1 | Device having one or more organic thin layers including luminescent layer between anode and cathode, wherein at least one layer contains selected compound or compounds; exhibits higher-luminance luminescence than conventional device | NEC CORPORATION (JP) | 2003-06-24 | — | — | US | disclosed |