Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 6/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115903 | 0.94 | F2 (0.46) | CA12CA1CA2CA4CA5A | |
| SCHEMBL7218890 | 0.93 | NTRK1 (0.40) | KDM4ENPC1RAB9AF2ALDH1A1 | |
| SCHEMBL7216788 | 0.93 | KDM4E (0.39) | KDM4ENPC1RAB9AF2ALDH1A1 | |
| SCHEMBL7222786 | 0.92 | NTRK1 (0.44) | KDM4ENPC1RAB9AF2ALDH1A1 | |
| SCHEMBL7216888 | 0.91 | F2 (0.37) | KDM4ENPC1RAB9AF2ALDH1A1 | |
| SCHEMBL7223673 | 0.90 | F2 (0.39) | KDM4ENPC1RAB9AF2ALDH1A1 | |
| SCHEMBL7224671 | 0.89 | NTRK1 (0.40) | KDM4ENPC1RAB9AF2ALDH1A1 | |
| SCHEMBL7217108 | 0.88 | CA12 (0.46) | CA12CA1CA2CA4CA5A | |
| SCHEMBL7118128 | 0.88 | F2 (0.49) | KDM4ENPC1RAB9AF2 | |
| SCHEMBL7120411 | 0.87 | F2 (0.46) | KDM4ENPC1RAB9AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6656956-B2 | Tryptase inhibitor; antiinflamamtory agents, antiallergens | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-02 | — | — | US | disclosed |