Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223876 | 0.82 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AMAPTGAA | |
| SCHEMBL11180515 | 0.81 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AMAPK1HTT | |
| SCHEMBL7224291 | 0.78 | KMT2A (0.59) | ALDH1A1NPC1RAB9AHTTMAPT | |
| SCHEMBL7224192 | 0.78 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AHTTMAPT | |
| SCHEMBL22599735 | 0.78 | KMT2A (0.51) | ALDH1A1NPC1RAB9AMAPK1HTT | |
| SCHEMBL7223930 | 0.77 | GAA (0.45) | ALDH1A1NPC1RAB9AMAPK1HTT | |
| SCHEMBL7225402 | 0.76 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AHTTMAPT | |
| SCHEMBL7219606 | 0.75 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AHTTGLA | |
| SCHEMBL7224249 | 0.75 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AMAPTGAA | |
| SCHEMBL7223760 | 0.75 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |