Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | GALR3 | O60755 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686558 | 0.85 | SMN1; SMN2 (0.46) | KMT2AMEN1SMN1; SMN2GALR3HTT | |
| SCHEMBL7224067 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1SMN1; SMN2GALR3HTT | |
| SCHEMBL3544173 | 0.80 | SMN1; SMN2 (0.51) | KMT2AMEN1SMN1; SMN2GALR3HTT | |
| SCHEMBL31125083 | 0.80 | SMN1; SMN2 (0.51) | KMT2AMEN1SMN1; SMN2GALR3HTT | |
| SCHEMBL7219189 | 0.78 | ALDH1A1 (0.45) | KMT2AMEN1SMN1; SMN2GALR3HTT | |
| SCHEMBL3597390 | 0.77 | SMN1; SMN2 (0.51) | KMT2AMEN1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10882422 | 0.77 | SMN1; SMN2 (0.51) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL7224330 | 0.77 | ALDH1A1 (0.72) | KMT2AMEN1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL7223876 | 0.77 | ALDH1A1 (0.52) | KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL520594 | 0.76 | SMN1; SMN2 (0.54) | KMT2AMEN1SMN1; SMN2GALR3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |