SCHEMBL721920

SCHEMBL721920

CC=[Ti](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33
CCL2 P13500 1/20 0.33
HTR6 P50406 1/20 0.33
HTR2A P28223 2/20 0.32
SIGMAR1 Q99720 2/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
NFKB1 P19838 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9226208 0.81 SIGMAR1 (0.35) BRD4CCL2HTR6HTR2ASIGMAR1
SCHEMBL2133566 0.80 BRD4 (0.34) BRD4CCL2HTR6HTR2ASIGMAR1
SCHEMBL3381692 0.79 BRD4 (0.36) BRD4CCL2HTR6HTR2ASIGMAR1
SCHEMBL1130888 0.79 BRD4 (0.33) BRD4CCL2HTR6HTR2ASIGMAR1
SCHEMBL393668 0.79 HTR2A (0.36) BRD4CCL2HTR6HTR2ASIGMAR1
SCHEMBL8754935 0.79 BRD4 (0.33) BRD4CCL2HTR6HTR2ASIGMAR1
SCHEMBL5909718 0.78
SCHEMBL7630353 0.77 SIGMAR1 (0.33) BRD4CCL2HTR6HTR2ASIGMAR1
SCHEMBL4457209 0.76 BRD4 (0.34) BRD4CCL2HTR6HTR2ASIGMAR1
SCHEMBL4470955 0.76 HTR2A (0.34) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0294942-B2 Solid catalyst for polymerizing an olefin MITSUI CHEMICALS INC (JP) 2002-05-08 EP claimed
EP-0474391-B1 Polyolefins NIPPON OIL CO LTD (JP) 1995-10-25 EP claimed
EP-0294942-B1 Solid catalyst for polymerizing an olefin MITSUI PETROCHEMICAL IND (JP) 1994-07-13 EP claimed
EP-0474391-A2 Polyolefins NIPPON OIL CO. LTD. (JP) 1992-03-11 EP claimed
EP-1661921-B1 Synthetic lubricating oil and lubricating oil composition thereof MITSUI CHEMICALS INC (JP) 2019-07-17 EP disclosed
US-9469701-B2 Polyethylene powder ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-10-18 US disclosed
US-20160137760-A1 Polyethylene Powder ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-05-19 US disclosed
US-8426613-B2 Synthesis of substituted tetrahydroindenyl complexes TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-04-23 US disclosed
EP-2570472-A1 LUBRICATING OIL COMPOSITION Mitsui Chemicals, Inc. (JP) 2013-03-20 EP disclosed
US-8373011-B2 Used in a base oil of lubricant having good low temperature fluidity, low evaporativity, and thermal stability and oxidation stability IDEMITSU KOSAN CO., LTD. (JP) 2013-02-12 US disclosed
US-8357765-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-22 US disclosed
US-20120264889-A1 PRODUCTION PROCESS OF OLEFIN POLYMERIZATION CATALYST AND OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-18 US disclosed
EP-0295312-A1 SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR ITS PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-21 EP disclosed
EP-0294942-A1 Solid catalyst for polymerizing an olefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-14 EP disclosed
EP-0287666-A1 PROCESS FOR POLYMERIZING OLEFINS Mitsui Chemicals, Inc. (JP) 1988-10-26 EP disclosed
EP-0285443-A1 Process for producing solid catalyst for polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-05 EP disclosed
EP-0283164-A2 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-21 EP disclosed
US-4769510-A ETHYLENEBIS HOECHST AKTIENGESELLSCHAFT (DE) 1988-09-06 US disclosed
EP-0279863-A1 CATALYST FOR POLYMERIZING ALPHA-OLEFIN AND POLYMERIZATION PROCESS MITSUI CHEMICALS, INC. (JP) 1988-08-31 EP disclosed
EP-0279586-A2 Finely divided aluminoxane, process for producing same and its use MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-08-24 EP disclosed