Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385138 | 0.79 | HTR6 (0.33) | SIGMAR1HTR2ABRD4CCL2HTR6 | |
| SCHEMBL2133566 | 0.79 | BRD4 (0.34) | SIGMAR1KDM4EHTR2ABRD4CCL2 | |
| SCHEMBL8754935 | 0.77 | BRD4 (0.33) | SIGMAR1KDM4EHTR2ABRD4CCL2 | |
| SCHEMBL1130888 | 0.77 | BRD4 (0.33) | SIGMAR1KDM4EHTR2ABRD4CCL2 | |
| SCHEMBL721920 | 0.77 | BRD4 (0.33) | SIGMAR1KDM4EHTR2ABRD4CCL2 | |
| SCHEMBL3381833 | 0.75 | HTR6 (0.33) | SIGMAR1HTR2ABRD4CCL2HTR6 | |
| SCHEMBL3385648 | 0.75 | HTR6 (0.33) | SIGMAR1HTR2ABRD4CCL2HTR6 | |
| SCHEMBL3385102 | 0.75 | HTR6 (0.33) | SIGMAR1HTR2ABRD4CCL2HTR6 | |
| Hydrochloric Acid SCHEMBL8605232 | 0.75 | SIGMAR1 (0.32) | SIGMAR1KDM4EHTR2ABRD4CCL2 | |
| SCHEMBL7628486 | 0.75 | SIGMAR1 (0.32) | SIGMAR1HTR2ABRD4CCL2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849288-B1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORP (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5906955-A | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1999-05-25 | — | — | US | disclosed |
| EP-0849288-A1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1998-06-24 | — | — | EP | disclosed |