Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 10/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7545753 | 0.92 | F10 (0.45) | DGAT1F10 | |
| Trifluoroacetic Acid SCHEMBL7409149 | 0.92 | F10 (0.45) | DGAT1F10 | |
| Trifluoroacetic Acid SCHEMBL6220788 | 0.92 | F10 (0.45) | DGAT1F10 | |
| Trifluoroacetic Acid SCHEMBL7213639 | 0.89 | DGAT1 (0.39) | DGAT1F10MAP4K4PDPK1IP6K1 | |
| Trifluoroacetic Acid SCHEMBL7213641 | 0.89 | DGAT1 (0.39) | DGAT1F10MAP4K4PDPK1IP6K1 | |
| Trifluoroacetic Acid SCHEMBL7219250 | 0.87 | F10 (0.41) | DGAT1F10MAP4K4PDPK1 | |
| Trifluoroacetic Acid SCHEMBL7921756 | 0.86 | F10 (0.43) | DGAT1F10MAP4K4 | |
| Trifluoroacetic Acid SCHEMBL7220555 | 0.86 | SMYD3 (0.39) | F10 | |
| Trifluoroacetic Acid SCHEMBL7452358 | 0.85 | F10 (0.40) | DGAT1F10MAP4K4PDPK1 | |
| Trifluoroacetic Acid SCHEMBL7540260 | 0.84 | F10 (0.48) | DGAT1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | claimed |
| US-6602864-B1 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |