Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | DPP4 | P27487 | 6/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7923392 | 0.92 | F10 (0.36) | SMYD3F10DPP4DPP7F2 | |
| SCHEMBL7921805 | 0.91 | F10 (0.42) | SMYD3F10F2NR4A2 | |
| Trifluoroacetic Acid SCHEMBL7220554 | 0.89 | MET (0.38) | SMYD3F10DPP4DPP7DPP8 | |
| Trifluoroacetic Acid SCHEMBL7219247 | 0.86 | DGAT1 (0.40) | F10 | |
| Trifluoroacetic Acid SCHEMBL7213657 | 0.84 | F10 (0.48) | F10DPP4DPP7F2 | |
| Trifluoroacetic Acid SCHEMBL7540260 | 0.84 | F10 (0.48) | F10DPP4DPP7F2 | |
| Trifluoroacetic Acid SCHEMBL7213717 | 0.84 | F10 (0.48) | F10DPP4DPP7F2 | |
| Trifluoroacetic Acid SCHEMBL7214506 | 0.82 | F10 (0.46) | F10F2 | |
| SCHEMBL7921783 | 0.82 | F10 (0.40) | F10F2NR4A2 | |
| SCHEMBL6224794 | 0.82 | F10 (0.40) | F10F2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |
| US-6602864-B1 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | disclosed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |