Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | RORC | P51449 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217674 | 0.81 | HPGD (0.53) | KMT2AMEN1SMN1; SMN2LMNATP53 | |
| SCHEMBL6811505 | 0.78 | KMT2A (0.74) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10836873 | 0.77 | KMT2A (0.72) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL17699316 | 0.77 | KMT2A (0.72) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10971067 | 0.76 | KMT2A (0.67) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL28493356 | 0.76 | KMT2A (0.71) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL29369092 | 0.76 | RORC (1.00) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1456273 | 0.76 | MAPT (0.71) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL420231 | 0.76 | RORC (1.00) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5079427 | 0.76 | MAPT (0.71) | KMT2AMEN1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |