Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225253 | 0.83 | GAA (0.47) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL8054041 | 0.83 | HPGD (0.57) | HPGDALDH1A1BCAT2MEN1KMT2A | |
| SCHEMBL7219266 | 0.81 | KMT2A (0.60) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL8042309 | 0.79 | HPGD (0.53) | HPGDALDH1A1BCAT2MEN1KMT2A | |
| SCHEMBL8055459 | 0.76 | KDM4E (0.42) | HPGDALDH1A1BCAT2KMT2AKDM4E | |
| SCHEMBL7217502 | 0.76 | HPGD (0.61) | HPGDALDH1A1BCAT2MEN1KMT2A | |
| SCHEMBL437231 | 0.74 | ALDH1A1 (0.87) | HPGDALDH1A1BCAT2MEN1KMT2A | |
| SCHEMBL8054126 | 0.73 | RAB9A (0.60) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6919153 | 0.72 | NAMPT (0.47) | HPGDBCAT2MEN1KMT2AKDM4E | |
| SCHEMBL11266257 | 0.72 | ALDH1A1 (0.83) | HPGDALDH1A1BCAT2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |