Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.83 |
| ▸ | ITGA2B | P08514 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219511 | 1.00 | ITGB3 (0.83) | ITGB3ITGA2B | |
| SCHEMBL7213400 | 0.91 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL6128667 | 0.88 | ITGB3 (0.76) | ITGB3ITGA2B | |
| SCHEMBL7213402 | 0.85 | ITGB3 (0.77) | ITGB3ITGA2B | |
| Roxifiban SCHEMBL24336949 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Roxifiban SCHEMBL344302 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Roxifiban SCHEMBL919675 | 0.84 | ITGB3 (0.95) | ITGB3ITGA2B | |
| SCHEMBL7376910 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2B | |
| SCHEMBL7375616 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2B | |
| SCHEMBL7220986 | 0.80 | ITGB3 (0.83) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6623981-B2 | Detecting antibodies which bind integrin bound modulators; obtain sample, incubate with modulators and antibodies, form complexes, screen for bound complex | BRISTOL-MYERS SQUIBB COMPANY | 2003-09-23 | — | — | US | disclosed |