Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215518 | 0.84 | CHRNB2 (0.42) | CYP11B1CYP11B2KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL31253097 | 0.82 | HRH4 (0.45) | CYP11B1CYP11B2HRH4MEN1MAPT | |
| SCHEMBL1641172 | 0.82 | HRH4 (0.45) | CYP11B1CYP11B2HRH4MEN1MAPT | |
| SCHEMBL21928132 | 0.71 | CYP11B1 (0.38) | CYP11B1CYP11B2KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL625135 | 0.70 | NOS3 (0.54) | CYP11B1CYP11B2KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL31695297 | 0.70 | NOS3 (0.54) | CYP11B1CYP11B2KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL21927209 | 0.69 | HRH4 (0.44) | CYP11B1CYP11B2HRH4MEN1MAPT | |
| SCHEMBL2716951 | 0.68 | HRH4 (0.41) | CYP11B1CYP11B2HRH4MEN1MAPT | |
| SCHEMBL2011637 | 0.68 | KDM4E (0.47) | MEN1KMT2AKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL22066216 | 0.67 | HTT (0.42) | CYP11B1CYP11B2KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |