Ether

Ether

SCHEMBL7219756

CCOCC.Nc1ccc(-c2cccc(N)c2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.55
TAAR1 Q96RJ0 2/20 0.48
CYP3A4 P08684 5/20 0.47
CYP19A1 P11511 3/20 0.47
CYP17A1 P05093 2/20 0.47
CYP11B1 P15538 2/20 0.47
CYP11B2 P19099 2/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
TP53 P04637 2/20 0.47
TDP1 Q9NUW8 2/20 0.45
HSD17B10 Q99714 1/20 0.45
MAP4K4 O95819 4/20 0.44
MEN1 O00255 2/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
GLA P06280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL7163808 1.00 MAOA (0.55) MAOATAAR1CYP3A4CYP19A1CYP17A1
Ether SCHEMBL20518532 0.92 MAOA (0.58) MAOACYP3A4CYP19A1CYP17A1CYP11B1
Propane SCHEMBL28332292 0.88 MAOA (0.64) MAOATAAR1CYP3A4CYP19A1CYP17A1
Proflavine SCHEMBL1660108 0.87 MEN1 (0.50) MAOATAAR1CYP3A4CYP19A1CYP17A1
Ether SCHEMBL1054057 0.86 MEN1 (0.48) MAOACYP3A4CYP19A1CYP17A1CYP11B1
Biphenyl-4-Amine SCHEMBL8808746 0.84 TDP1 (0.65) MAOATAAR1CYP3A4TP53TDP1
Benzidine SCHEMBL1056565 0.84 TDP1 (0.58) MAOATAAR1CYP3A4CYP19A1CYP17A1
SCHEMBL29350106 0.84 MAOA (0.76) MAOATAAR1CYP3A4CYP19A1CYP17A1
SCHEMBL250353 0.84 MAOA (0.76) MAOATAAR1CYP3A4CYP19A1CYP17A1
SCHEMBL29115269 0.84 MAOA (0.76) MAOATAAR1CYP3A4CYP19A1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331927-A1 POLYMETALLOXANE-CONTAINING COMPOSITION, CURED BODY, MEMBER, ELECTRONIC COMPONENT, AND FIBER TORAY INDUSTRIES, INC. (JP) 2023-10-19 US disclosed
US-6627377-B1 Soluble in organic solvents, which excels in adhesiveness, heat resistance, mechanical properties and flexibility, which shows properties of alkali-soluble highly sensitive positive-type photoresist PI R&D CO., LTD. (JP) 2003-09-30 US disclosed
EP-1024407-A1 POSITIVE PHOTOSENSITIVE POLYIMIDE COMPOSITION PI R & D Co Ltd (JP) 2000-08-02 EP disclosed
US-5665802-A REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-09-09 US disclosed
EP-0350958-B1 Improved polyimide and polyimide film and manufacturing method thereof KANEGAFUCHI CHEMICAL IND (JP) 1994-12-21 EP disclosed