Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218670 | 0.78 | MEN1 (0.43) | MEN1KMT2ACYP1A2 | |
| SCHEMBL7627312 | 0.73 | NAAA (0.40) | DUTKCNN4 | |
| SCHEMBL7627317 | 0.73 | NAAA (0.40) | DUTKCNN4 | |
| SCHEMBL6067809 | 0.73 | ALDH1A1 (0.48) | CYP2D6MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL7463203 | 0.73 | ALDH1A1 (0.48) | CYP2D6MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL5898896 | 0.73 | DDB1 (0.59) | DDB1CRBNMEN1KMT2AGAA | |
| SCHEMBL3460233 | 0.72 | ALDH1A1 (0.53) | KDM4ENPC1RAB9A | |
| SCHEMBL7804797 | 0.72 | ALDH1A1 (0.53) | KDM4ENPC1RAB9A | |
| SCHEMBL5401841 | 0.72 | ALDH1A1 (0.53) | KDM4ENPC1RAB9A | |
| SCHEMBL9811435 | 0.71 | KCNN4 (0.34) | DUTDDB1CRBNKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660734-B1 | Oxazinones having antibacterial activity | SIMON FRASER UNIVERSITY (CA) | 2003-12-09 | — | — | US | disclosed |
| US-6399600-B1 | ANTIBIOTIC RESISTANT BATERIA INFECTIONS | SIMON FRASER UNIVERSITY (CA) | 2002-06-04 | — | — | US | disclosed |