Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 9/20 | 0.54 |
| ▸ | CES1 | P23141 | 9/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501781 | 0.95 | CES2 (0.56) | CES2CES1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL27844978 | 0.89 | CES2 (0.52) | CES2CES1POLBLMNAMAPT | |
| SCHEMBL8733899 | 0.82 | PGR (0.51) | CES2CES1POLBLMNAMAPT | |
| SCHEMBL4994418 | 0.82 | PGR (0.51) | CES2CES1POLBLMNAMAPT | |
| SCHEMBL28700778 | 0.82 | CES2 (0.53) | CES2CES1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL27614814 | 0.80 | CES2 (0.51) | CES2CES1POLBLMNAMAPT | |
| SCHEMBL6424289 | 0.77 | CES2 (0.50) | CES2CES1LMNAALDH1A1CNR2 | |
| SCHEMBL6686403 | 0.76 | CES2 (0.51) | CES2CES1ALDH1A1CNR2PRSS1 | |
| SCHEMBL6683969 | 0.76 | CES2 (0.51) | CES2CES1ALDH1A1CNR2PRSS1 | |
| SCHEMBL1195165 | 0.76 | CES2 (0.51) | CES2CES1ALDH1A1CNR2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |