Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219112 | 0.77 | ADORA1 (0.53) | ALDH1A1KDM4EHTTRXFP1LMNA | |
| SCHEMBL28026305 | 0.76 | MEN1 (0.53) | ALDH1A1KDM4ETHRBMAPTMEN1 | |
| SCHEMBL31663512 | 0.76 | ADORA1 (0.49) | ALDH1A1KDM4EHTTLMNAMEN1 | |
| SCHEMBL31663547 | 0.74 | KMT2A (0.48) | ALDH1A1KDM4EHTTRXFP1LMNA | |
| SCHEMBL13203110 | 0.74 | MEN1 (0.52) | ALDH1A1KDM4ETHRBMAPTMEN1 | |
| SCHEMBL1343029 | 0.74 | ESR1 (0.58) | ALDH1A1KDM4EHTTLMNATHRB | |
| SCHEMBL29672194 | 0.74 | ADORA1 (0.58) | ALDH1A1KDM4EHTTRXFP1LMNA | |
| SCHEMBL7213476 | 0.74 | MYC (0.54) | ALDH1A1KDM4ELMNAMAPTGAA | |
| SCHEMBL13203040 | 0.73 | MEN1 (0.50) | ALDH1A1KDM4ERXFP1LMNATHRB | |
| SCHEMBL13203307 | 0.73 | MEN1 (0.50) | ALDH1A1KDM4ETHRBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |