SCHEMBL7213476

SCHEMBL7213476

N#Cc1cc(-c2ccccc2)nc(-c2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.54
L3MBTL1 Q9Y468 3/20 0.53
ADORA2A P29274 2/20 0.53
ADORA1 P30542 2/20 0.53
MAPK1 P28482 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
KDM4E B2RXH2 2/20 0.53
ABCG2 Q9UNQ0 2/20 0.53
LMNA P02545 1/20 0.53
SLC6A2 P23975 1/20 0.51
SLC6A4 P31645 1/20 0.51
KCNH2 Q12809 1/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
GABRA1 P14867 2/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRA5 P31644 2/20 0.50
GABRA3 P34903 2/20 0.50
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663595 0.86 L3MBTL1 (0.54) MYCL3MBTL1ADORA2AADORA1MAPK1
SCHEMBL31663589 0.83 GABRG2 (0.67) MYCADORA2AADORA1GABRA1GABRG2
SCHEMBL31273466 0.83 GABRG2 (0.67) MYCADORA2AADORA1GABRA1GABRG2
SCHEMBL31273727 0.81 GABRG2 (0.65) MYCADORA2AADORA1GABRA1GABRG2
SCHEMBL10431256 0.80 GABRA1 (0.59) ADORA2AADORA1MAPK1MEN1KMT2A
SCHEMBL17462008 0.79 ALDH1A1 (0.52) MYCL3MBTL1ADORA2AADORA1SMN1; SMN2
SCHEMBL31663506 0.79 CLK4 (0.61) ADORA2AADORA1MAPK1KDM4EABCG2
SCHEMBL31663525 0.79 ABCG2 (0.50) L3MBTL1ADORA2AADORA1MAPK1SMN1; SMN2
SCHEMBL22563481 0.79 ABCG2 (0.50) MYCL3MBTL1ADORA2AADORA1MAPK1
SCHEMBL20911800 0.79 HPGD (0.50) MYCL3MBTL1ADORA2AADORA1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6603007-B1 Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence SANKIO CHEMICAL CO., LTD. (JP) 2003-08-05 US disclosed
EP-1231207-A1 NOVEL BIPYRIDYL DERIVATIVES Sankio Chemical Co., Ltd. (JP) 2002-08-14 EP disclosed