Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663536 | 0.81 | GABRG2 (0.50) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL31273715 | 0.81 | GABRG2 (0.50) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL3089787 | 0.81 | ADORA2A (0.53) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL15832003 | 0.79 | ADORA1 (0.51) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL5329336 | 0.79 | ADORA1 (0.56) | ADORA1ADORA2AKDM4EALDH1A1MEN1 | |
| SCHEMBL1904903 | 0.79 | CYP1A2 (0.53) | KDM4EALDH1A1LMNAHTTRXFP1 | |
| SCHEMBL19805092 | 0.79 | MEN1 (0.50) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL19313661 | 0.78 | ADORA1 (0.47) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL29672194 | 0.78 | ADORA1 (0.58) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL7220074 | 0.77 | ALDH1A1 (0.47) | ADORA1ADORA2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |