SCHEMBL7220225

SCHEMBL7220225

COC(=O)C(C)Oc1ccc(CO)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MAPT P10636 2/20 0.49
PPARG P37231 2/20 0.46
PPARA Q07869 2/20 0.46
TSHR P16473 2/20 0.46
ALDH2 P05091 1/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TAS1R3 Q7RTX0 1/20 0.45
TAS1R1 Q7RTX1 1/20 0.45
TAS1R2 Q8TE23 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KLK7 P49862 1/20 0.44
EPHX2 P34913 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4250581 0.87 KMT2A (0.58) KMT2AMEN1L3MBTL1MAPTTSHR
SCHEMBL1453865 0.85 LMNA (0.62) KMT2AMEN1L3MBTL1MAPTPPARG
SCHEMBL14122341 0.85 KMT2A (0.48) KMT2AMEN1L3MBTL1MAPTTSHR
SCHEMBL14122340 0.85 KMT2A (0.48) KMT2AMEN1L3MBTL1MAPTTSHR
SCHEMBL7848021 0.85 KMT2A (0.51) KMT2AMEN1L3MBTL1MAPTTSHR
SCHEMBL14122523 0.85 KMT2A (0.48) KMT2AMEN1L3MBTL1MAPTTSHR
SCHEMBL4268398 0.83 CYP4F2 (0.51) KMT2AMEN1L3MBTL1MAPTTSHR
SCHEMBL8880123 0.83 POLB (0.68) KMT2AMEN1L3MBTL1MAPTTSHR
SCHEMBL7993446 0.82 CYP1A2 (0.61) PPARGPPARAPOLBSMN1; SMN2EPHX2
SCHEMBL2174618 0.82 ALDH1A1 (0.47) L3MBTL1MAPTTSHRALDH2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664214-B1 Uracil compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-16 US disclosed
EP-0656892-B1 HERBICIDAL 2- (4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORP (US) 2001-06-13 EP disclosed
US-5798316-A GRASS OR BROADLEAF CONTROLLING AGENTS FMC CORPORATION 1998-08-25 US disclosed
US-5674810-A MIXTURE OF TWO HERBICIDES WITH DIFFERENT STRUCTURES, CARRIER FMC CORPORATION (US) 1997-10-07 US disclosed
CN-1035434-C Herbicidal 2-[(4-heterocyclic-phenoxymethyl) phenoxy]-alkanoates FMC CORP (US) 1997-07-16 CN disclosed
WO-1997008953-A1 HERBICIDAL 2-[(4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORPORATION (US) 1997-03-13 WO disclosed
EP-0656892-A1 HERBICIDAL 2- (4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORPORATION (US) 1995-06-14 EP disclosed
US-5344812-A 1-methyl-6 -trifluoromethyl-2,4-pyrimidinedione-3-yl derivative as plant growth regulators FMC CORPORATION (US) 1994-09-06 US disclosed
CN-1083479-A 2-[(4-heterocycle-phenoxymethyl) phenoxy group] the alkanoates weedicide FMC CORP (US) 1994-03-09 CN disclosed
WO-1994004514-A1 HERBICIDAL 2-[(4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORPORATION (US) 1994-03-03 WO disclosed
US-5262390-A PLANT GROWTH REGULATORS FMC CORPORATION (US) 1993-11-16 US disclosed
US-4169720-A 2-[4-(4-Chlorophenoxymethyl)-phenoxy]-propionic acid compounds as herbicides CELAMERCK GMBH & CO. KG (DE) 1979-10-02 US disclosed