SCHEMBL722048

SCHEMBL722048

CCCc1ccc(C(=O)O)c(C(=O)O)c1CC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.44
PTPN11 Q06124 2/20 0.44
PRKCI P41743 1/20 0.40
PTPN2 P17706 1/20 0.38
LDHA P00338 2/20 0.37
LDHB P07195 2/20 0.37
GABRP O00591 2/20 0.37
GABRD O14764 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB1 P18505 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
GABRA5 P31644 2/20 0.37
GABRA3 P34903 2/20 0.37
GABRA2 P47869 2/20 0.37
GABRB2 P47870 2/20 0.37
GABRA4 P48169 2/20 0.37
GABRE P78334 2/20 0.37
GABRA6 Q16445 2/20 0.37
GABRG1 Q8N1C3 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136572 0.91 PTPN1 (0.45) PTPN1PTPN11PRKCILDHALDHB
SCHEMBL19066308 0.91 PTPN1 (0.45) PTPN1PTPN11PRKCILDHALDHB
SCHEMBL724313 0.90 BID (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL75798 0.89 ALDH1A1 (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL722049 0.88 PTPN1 (0.41) PTPN1PTPN11PRKCILDHALDHB
SCHEMBL17911667 0.87 GABRP (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL5519813 0.87 PPARA (0.52) MCL1BIDBCL2L1BAK1PPARA
SCHEMBL5519595 0.87 PPARA (0.52) MCL1BIDBCL2L1BAK1PPARA
SCHEMBL5528728 0.87 PPARA (0.52) MCL1BIDBCL2L1BAK1PPARA
SCHEMBL5518763 0.87 PPARA (0.52) MCL1BIDBCL2L1BAK1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878659-B2 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2005-04-12 US claimed
US-8648001-B2 Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same TOHO TITANIUM CO., LTD. (JP) 2014-02-11 US disclosed
US-20120053310-A1 Aminosilane Compounds, Catalyst Components and Catalysts for Olefin Polymerization, and Process for Production of Olefin Polymers with the Same TOHO TITANIUM CO., LTD. (JP) 2012-03-01 US disclosed
US-7208435-B2 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2007-04-24 US disclosed
US-7141634-B2 Catalyst for olefin polymerization and process for polymerizing olefins TOHO CATALYST CO., LTD. (JP) 2006-11-28 US disclosed
US-6878659-B2 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2005-04-12 US disclosed
US-20050054773-A1 Solid catalyst component for olefin polymerization, catalyst, and propylene block copolymer TOHO CATALYST CO, LTD. (JP) 2005-03-10 US disclosed