Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.67 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.67 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.67 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598485 | 1.00 | GNAI3 (0.67) | GNAI3GNAO1GNAI1SPHK1DRD2 | |
| Hydrochloric Acid SCHEMBL25362599 | 0.98 | GNAI3 (0.70) | GNAI3GNAO1GNAI1SPHK1DRD2 | |
| Propylamine SCHEMBL7227689 | 0.93 | GNAI3 (0.60) | GNAI3GNAO1GNAI1SPHK1DRD2 | |
| Dimethylamine SCHEMBL8113230 | 0.93 | GNAI3 (0.60) | GNAI3GNAO1GNAI1SPHK1DRD2 | |
| Dimethylamine SCHEMBL6939835 | 0.93 | GNAI3 (0.60) | GNAI3GNAO1GNAI1SPHK1DRD2 | |
| Diethylamine SCHEMBL6945135 | 0.89 | GNAI3 (0.56) | GNAI3GNAO1GNAI1SPHK1DRD2 | |
| SCHEMBL6941401 | 0.88 | GNAI3 (0.55) | GNAI3GNAO1GNAI1SPHK1DRD2 | |
| SCHEMBL6941884 | 0.86 | GNAO1 (0.81) | GNAI3GNAO1GNAI1SPHK1 | |
| SCHEMBL13102165 | 0.86 | — | — | |
| SCHEMBL13102164 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642231-B2 | Antineoplastic agents, treatment for neuronal injury and degeneration | AVENTIS PHARMACEUTICALS INC. | 2003-11-04 | — | — | US | disclosed |