SCHEMBL7220760

SCHEMBL7220760

Cc1[c]nc(-c2cccs2)s1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.44
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 2/20 0.44
EPHX2 P34913 1/20 0.44
RAB9A P51151 5/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
NPC1 O15118 2/20 0.42
KMT2A Q03164 6/20 0.42
HPGD P15428 4/20 0.42
MEN1 O00255 4/20 0.42
MAPT P10636 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
GAA P10253 2/20 0.40
GLA P06280 1/20 0.40
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1435544 0.71 SMN1; SMN2 (0.41) ALDH1A1RAB9ANPC1HPGDMAPT
SCHEMBL11701666 0.69 KDM4E (0.61) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL11991177 0.69 KDM4E (0.73) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL10091957 0.68 KDM4E (0.61) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL299064 0.68 KDM4E (0.46) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL354651 0.67 KDM4E (0.46) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL694479 0.67 KDM4E (0.46) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL144406 0.66 ALDH1A1 (0.53) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL2375004 0.66 KDM4E (0.58) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL1460693 0.66 KDM4E (0.53) KDM4EALDH1A1HSD17B10RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6605631-B1 Controlling fungi and pests; improved activity and plant tolerability BASF AKTIENGESELLSCHAFT (DE) 2003-08-12 US disclosed