SCHEMBL144406

SCHEMBL144406

Cc1ccc(-c2cccs2)s1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
KDM4E B2RXH2 6/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
MAPT P10636 3/20 0.53
LMNA P02545 2/20 0.53
GAA P10253 2/20 0.53
GLA P06280 1/20 0.53
LTA4H P09960 1/20 0.52
DPP4 P27487 4/20 0.50
NPC1 O15118 4/20 0.47
RAB9A P51151 3/20 0.47
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 2/20 0.47
HPGD P15428 2/20 0.47
KMT2A Q03164 2/20 0.47
TP53 P04637 1/20 0.47
POLB P06746 1/20 0.47
NFKB1 P19838 1/20 0.47
MAPK1 P28482 1/20 0.47
CASP1 P29466 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16785690 0.98 DPP4 (0.53) ALDH1A1KDM4EL3MBTL1MAPTLMNA
SCHEMBL16785691 0.98 DPP4 (0.53) ALDH1A1KDM4EL3MBTL1MAPTLMNA
SCHEMBL498537 0.98 DPP4 (0.53) ALDH1A1KDM4EL3MBTL1MAPTLMNA
SCHEMBL16785688 0.98 DPP4 (0.53) ALDH1A1KDM4EL3MBTL1MAPTLMNA
SCHEMBL16785692 0.98 DPP4 (0.53) ALDH1A1KDM4EL3MBTL1MAPTLMNA
SCHEMBL14437828 0.98 DPP4 (0.53) ALDH1A1KDM4EL3MBTL1MAPTLMNA
SCHEMBL13144214 0.89 DPP4 (0.46) ALDH1A1KDM4EL3MBTL1MAPTLMNA
SCHEMBL20371369 0.87 DPP4 (0.57) ALDH1A1KDM4EL3MBTL1MAPTLMNA
SCHEMBL12744124 0.85 LTA4H (0.50) ALDH1A1KDM4EL3MBTL1MAPTLMNA
SCHEMBL24141652 0.84 LTA4H (0.48) ALDH1A1KDM4EL3MBTL1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4060528-A ANTIINFLAMMATORY JANSSEN PHARMACEUTICA N.V. (BE) 1977-11-29 US claimed
US-12040140-B2 Coatings for electronic devices, solar cells, composite materials, and methods The Florida State University Research Foundation, Inc. (US) 2024-07-16 US disclosed
US-12040140-B2 Coatings for electronic devices, solar cells, composite materials, and methods The Florida State University Research Foundation, Inc. (US) 2024-07-16 US disclosed
WO-2024010732-A1 SMALL MOLECULE INHIBITORS OF GLUTAMINE TRANSPORTER ASCT2 AND METHODS OF USE THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-01-11 WO disclosed
US-11858911-B2 Squarylium compounds and infrared cut films, infrared cut filters and electronic devices including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-02 US disclosed
US-11858911-B2 Squarylium compounds and infrared cut films, infrared cut filters and electronic devices including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-02 US disclosed
US-20230320212-A1 ORGANIC SEMICONDUCTOR MIXTURE AND ORGANIC OPTOELECTRONIC DEVICE CONTAINING THE SAME Raynergy Tek Incorporation (TW) 2023-10-05 US disclosed
US-20230301984-A1 CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-09-28 US disclosed
US-20230301984-A1 CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-09-28 US disclosed
EP-2764034-B1 POLYMERS BASED ON BENZODIONES CLAP CO LTD (KR) 2023-08-30 EP disclosed
WO-2007003520-A1 FLUORESCENT DIKETOPYRROLOPYRROLES AND DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-11 WO disclosed
US-20070010672-A1 Fluorescent diketopyrrolopyrroles CLAP CO., LTD. (KR) 2007-01-11 US disclosed
US-20070010672-A1 Fluorescent diketopyrrolopyrroles CLAP CO., LTD. (KR) 2007-01-11 US disclosed
WO-2006077412-A1 THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION BIOLIPOX AB (SE) 2006-07-27 WO disclosed
WO-2003048109-A1 NOVEL GLUCAGON ANTAGONISTS NOVO NORDISK A/S (DK) 2003-06-12 WO disclosed
EP-0454204-B1 Method for the photochemical isomeration of organic compounds under the influence of a photosensitizer DUPHAR INT RES (NL) 1995-06-28 EP disclosed
US-5252191-A Method for the photochemical isomerization of organic compounds under the influence of a photosensitizer DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1993-10-12 US disclosed
EP-0454204-A2 Method for the photochemical isomeration of organic compounds under the influence of a photosensitizer DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1991-10-30 EP disclosed
US-4826829-A MITICIDES FMC CORPORATION (US) 1989-05-02 US disclosed
WO-1988000467-A1 2-SUBSTITUTED ETHYNYL THIOPHENE PESTICIDES FMC CORPORATION (US) 1988-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320212-A1 ORGANIC SEMICONDUCTOR MIXTURE AND ORGANIC OPTOELECTRONIC DEVICE CONTAINING THE SAME OSTC, NONO, OR10J3 ALDH1A1 3861/4885KDM4E 2703/4885L3MBTL1 3030/4885
US-20230301984-A1 CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION ALDH1A2, PDE6D, PDE6C ALDH1A1 145/4885KDM4E 3316/4885L3MBTL1 1268/4885
US-20070010672-A1 Fluorescent diketopyrrolopyrroles TYR, QDPR, MC1R ALDH1A1 842/4885KDM4E 205/4885L3MBTL1 4503/4885
US-11858911-B2 Squarylium compounds and infrared cut films, infrared cut filters and electronic devices including the same CUTA, SQLE, HMGCR ALDH1A1 1585/4885KDM4E 1469/4885L3MBTL1 3737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.