Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221093 | 0.81 | MEN1 (0.40) | KDM4EHPGDKMT2APOLBCYP3A4 | |
| SCHEMBL7220255 | 0.78 | KMT2A (0.41) | KDM4EALDH1A1GAAHPGDKMT2A | |
| SCHEMBL7214201 | 0.76 | ALDH1A1 (0.34) | KDM4EALDH1A1GAAHPGDKMT2A | |
| SCHEMBL2279251 | 0.70 | KDM4E (0.62) | KDM4EALDH1A1GAAHPGDKMT2A | |
| SCHEMBL1062838 | 0.67 | KDM4E (1.00) | KDM4EALDH1A1HPGDNR1H2NR1H3 | |
| SCHEMBL5599861 | 0.67 | HCAR2 (0.61) | TSHR | |
| SCHEMBL7454496 | 0.67 | TSHR (0.39) | KDM4EALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL853412 | 0.67 | GAA (0.46) | KDM4EALDH1A1GAAHPGDKMT2A | |
| SCHEMBL13962639 | 0.66 | TSHR (0.39) | ALDH1A1GAAHPGDKMT2ATSHR | |
| SCHEMBL8009875 | 0.66 | TSHR (0.49) | KDM4EALDH1A1GAAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |