Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220910 | 0.76 | KDM4E (0.50) | ALDH1A1KDM4EHPGDGAAKMT2A | |
| SCHEMBL7440360 | 0.74 | HSD11B1 (0.34) | KMT2ANPC1CXCR2HSD11B1TSHR | |
| SCHEMBL7220255 | 0.69 | KMT2A (0.41) | ALDH1A1KDM4EHPGDGAAKMT2A | |
| SCHEMBL7214195 | 0.68 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDKMT2ATSHR | |
| SCHEMBL1821726 | 0.67 | CXCR2 (0.61) | KMT2APOLBCXCR2CXCR1HSD17B10 | |
| SCHEMBL7440362 | 0.67 | MAPK1 (0.38) | ALDH1A1KDM4EHPGDGAAKMT2A | |
| SCHEMBL7445980 | 0.66 | HSD17B10 (0.42) | ALDH1A1KDM4EHPGDGAAKMT2A | |
| SCHEMBL2380488 | 0.66 | HSD11B1 (0.44) | ALDH1A1HPGDKMT2APOLBCXCR2 | |
| SCHEMBL4752944 | 0.65 | SMN1; SMN2 (0.47) | ALDH1A1KDM4EHPGDGAAKMT2A | |
| SCHEMBL9080409 | 0.65 | TSHR (0.43) | ALDH1A1KDM4EGAAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |