Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216462 | 0.88 | F2 (0.45) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7139116 | 0.76 | KDM4E (0.45) | MEN1KMT2AALDH1A1KDM4EF2 | |
| SCHEMBL5474623 | 0.75 | F2 (0.52) | MEN1KMT2AALDH1A1KDM4EF2 | |
| SCHEMBL7158554 | 0.74 | F2 (0.63) | F2PRSS1 | |
| SCHEMBL7214888 | 0.74 | F2 (0.67) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3238629 | 0.73 | F2 (0.46) | MEN1KMT2AALDH1A1F2PRSS1 | |
| SCHEMBL5479394 | 0.73 | F2 (0.50) | MEN1KMT2AF2PRSS1 | |
| SCHEMBL5474694 | 0.72 | F2 (0.64) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6957416 | 0.72 | F2 (0.70) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7449500 | 0.71 | MAPT (0.41) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |