Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.54 |
| ▸ | RXRG | P48443 | 10/20 | 0.40 |
| ▸ | RXRB | P28702 | 11/20 | 0.37 |
| ▸ | RARB | P10826 | 5/20 | 0.37 |
| ▸ | RARG | P13631 | 4/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080909 | 0.81 | RXRA (0.62) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL3633427 | 0.80 | RXRA (0.65) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7088008 | 0.79 | RXRA (0.61) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7220993 | 0.78 | RXRA (0.45) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7080041 | 0.77 | RXRA (0.56) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7800113 | 0.76 | RXRA (0.58) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7081365 | 0.75 | RXRA (0.49) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7083909 | 0.74 | RXRA (0.56) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL29374183 | 0.74 | RXRA (0.63) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL112943 | 0.74 | RXRA (0.63) | RXRARXRGRXRBRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642273-B2 | Dermatology, vision defects, cardiovascular disorders, antiinflammatory | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-11-04 | — | — | US | claimed |