Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.45 |
| ▸ | RXRG | P48443 | 6/20 | 0.41 |
| ▸ | RXRB | P28702 | 7/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080912 | 0.82 | RXRA (0.47) | RXRARXRGRXRBRARARARB | |
| SCHEMBL7220989 | 0.78 | RXRA (0.54) | RXRARXRGRXRBRARARARB | |
| SCHEMBL7081366 | 0.75 | RXRA (0.40) | RXRARXRGRXRBRARARARB | |
| SCHEMBL3633427 | 0.74 | RXRA (0.65) | RXRARXRGRXRBRARARARB | |
| SCHEMBL7085818 | 0.72 | RXRA (0.46) | RXRARXRGRXRB | |
| SCHEMBL31276766 | 0.70 | RXRA (0.50) | RXRARXRGRXRB | |
| SCHEMBL13696047 | 0.70 | RXRA (0.50) | RXRARXRGRXRB | |
| SCHEMBL112943 | 0.68 | RXRA (0.63) | RXRARXRGRXRBRARARARB | |
| SCHEMBL7081356 | 0.68 | RXRA (0.50) | RXRARXRGRXRB | |
| SCHEMBL29374183 | 0.68 | RXRA (0.63) | RXRARXRGRXRBRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642273-B2 | Dermatology, vision defects, cardiovascular disorders, antiinflammatory | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-11-04 | — | — | US | claimed |