SCHEMBL722108

SCHEMBL722108

CCOC(C)OCC.O=c1cc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.38
THRB P10828 1/20 0.36
PKM P14618 1/20 0.36
PTGS2 P35354 7/20 0.34
ACHE P22303 6/20 0.34
BCHE P06276 5/20 0.34
NQO1 P15559 1/20 0.32
EPHX1 P07099 1/20 0.32
PTPRC P08575 1/20 0.31
CDC25B P30305 1/20 0.31
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
PPARA Q07869 2/20 0.30
POLB P06746 1/20 0.30
APLNR P35414 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5670902 1.00 LMNA (0.63) LMNAL3MBTL1THRBPKMPTGS2
Benzoquinone SCHEMBL18838186 0.82 LMNA (0.60) LMNAL3MBTL1THRBPKMPTGS2
SCHEMBL9459 0.80
SCHEMBL2094168 0.80 LMNA (1.00) LMNATHRB
SCHEMBL2698061 0.79 LMNA (0.63) LMNATHRBPTGS2ACHEBCHE
SCHEMBL4918898 0.78 LMNA (0.55) LMNAL3MBTL1
Formaldehyde SCHEMBL209588 0.77 LMNA (0.80) LMNATHRB
Naphthoquinone SCHEMBL6917183 0.77 CDC25B (0.54) LMNAL3MBTL1THRBPKMPTPRC
SCHEMBL5105333 0.76
SCHEMBL3453066 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8157469-A None JP disclosed
JP-8198869-A None JP disclosed
JP-8198869-A None JP disclosed
JP-8198868-A None JP disclosed
JP-8198868-A None JP disclosed
EP-3978537-B1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER UNIV TOKYO (JP) 2023-09-13 EP disclosed
CN-113874402-B Polar group-containing olefin copolymer 国立大学法人东京大学 2023-04-04 CN disclosed
US-20220220239-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER THE UNIVERSITY OF TOKYO (JP) 2022-07-14 US disclosed
WO-2020241715-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER 国立大学法人東京大学 2020-12-03 WO disclosed
US-8541625-B2 Cyclopropenones and the photochemical generation of cyclic alkynes therefrom UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2013-09-24 US disclosed
EP-1069107-B1 FULLERENE DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 2005-05-11 EP disclosed
US-20040214218-A1 Fullerene derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-10-28 US disclosed
US-6765098-B1 DNA COMPACTION; GENE THERAPY FUJISAWA PHARMACEUTICAL CO., LTD (JP) 2004-07-20 US disclosed
EP-1420066-A2 Use of fullerene derivatives as DNA compaction agent FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-05-19 EP disclosed
EP-1069107-A1 FULLERENE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-01-17 EP disclosed
JP-H08198869-A PRODUCTION OF CYCLOPROPENONE ACETAL DERIVATIVE MITSUBISHI CHEM CORP 1996-08-06 JP disclosed
JP-H08198869-A PRODUCTION OF CYCLOPROPENONE ACETAL DERIVATIVE MITSUBISHI CHEM CORP 1996-08-06 JP disclosed
JP-H08198868-A PRODUCTION OF CYCLOPROPENONE ACETAL DERIVATIVE MITSUBISHI CHEM CORP 1996-08-06 JP disclosed
JP-H08198868-A PRODUCTION OF CYCLOPROPENONE ACETAL DERIVATIVE MITSUBISHI CHEM CORP 1996-08-06 JP disclosed
JP-H08157469-A PRODUCTION OF CYCLOPROPANONE ACETAL DERIVATIVE MITSUBISHI CHEM CORP 1996-06-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040214218-A1 Fullerene derivatives RCC1, TOP2A, DNAH12 LMNA 444/4885L3MBTL1 307/4885THRB 3682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.