Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13295547 | 0.89 | NR3C1 (0.58) | AHRNR3C1PGRNR3C2AR | |
| SCHEMBL13295548 | 0.89 | NR3C1 (0.50) | AHRNR3C1PGRNR3C2AR | |
| SCHEMBL29368878 | 0.87 | ALDH1A1 (0.51) | KMT2ANQO1GAAALDH1A1SLC6A4 | |
| SCHEMBL333444 | 0.87 | ALDH1A1 (0.51) | KMT2ANQO1GAAALDH1A1SLC6A4 | |
| SCHEMBL7221231 | 0.84 | AHR (0.49) | AHRNR3C1PGRNR3C2AR | |
| SCHEMBL7221229 | 0.80 | KMT2A (0.48) | AHRKMT2ARAB9ANPC1GAA | |
| SCHEMBL14564174 | 0.79 | ELANE (0.47) | AHRKMT2AGAAALDH1A1KDM4E | |
| SCHEMBL28812693 | 0.78 | HPRT1 (0.47) | KMT2ANQO1GAAALDH1A1MEN1 | |
| SCHEMBL5024819 | 0.77 | ACP3 (0.56) | NR3C1PGRNR3C2ARLTA4H | |
| SCHEMBL4457608 | 0.77 | KMT2A (0.48) | AHRNR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | disclosed |