Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 20/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 19/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 19/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5089281 | 0.92 | ADORA2A (0.53) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5094362 | 0.86 | ADORA3 (0.54) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7231095 | 0.84 | ADORA2A (0.67) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7231864 | 0.84 | ADORA3 (0.42) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5094417 | 0.84 | ADORA2A (0.48) | ADORA3ADORA2AADORA1ADORA2B | |
| Formic Acid SCHEMBL7452270 | 0.83 | ADORA3 (0.51) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5094390 | 0.83 | ADORA2A (0.48) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7742184 | 0.83 | PGK1 (0.57) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5088096 | 0.83 | PGK1 (0.57) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5086172 | 0.82 | ADORA2A (0.71) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528494-B2 | Antiinflammatory agents | COX BRIAN (GB) | 2003-03-04 | — | — | US | disclosed |