Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.40 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071274 | 0.90 | USP30 (0.53) | USP30PTPN1CYP3A4SLC6A3KCNH2 | |
| SCHEMBL7224996 | 0.89 | USP30 (0.42) | USP30GSK3BPTPN1PTPN11SLC6A3 | |
| Hydrochloric Acid SCHEMBL7075524 | 0.89 | USP30 (0.52) | USP30PTPN1CYP3A4SLC6A3KCNH2 | |
| SCHEMBL7233080 | 0.89 | USP30 (0.43) | USP30CYP3A4NPC1ALDH1A1MAPT | |
| SCHEMBL7231198 | 0.88 | SMN1; SMN2 (0.47) | USP30PTPN1PTPN11SLC6A3NPC1 | |
| SCHEMBL7234180 | 0.88 | USP30 (0.42) | USP30PTPN1PTPN11SLC6A3KCNH2 | |
| SCHEMBL7225141 | 0.88 | USP30 (0.44) | CDC7DBF4USP30PTPN1PTPN11 | |
| SCHEMBL7223371 | 0.88 | USP30 (0.42) | USP30GSK3BPTPN1PTPN11SLC6A3 | |
| SCHEMBL7226143 | 0.88 | PTPN11 (0.49) | USP30PTPN1PTPN11SLC6A3 | |
| SCHEMBL7233210 | 0.88 | GSK3B (0.41) | USP30GSK3BPTPN11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |