Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224996 | 0.90 | USP30 (0.42) | USP30SLC6A3PTPN1PTPN11HDAC1 | |
| SCHEMBL7226045 | 0.90 | USP30 (0.43) | USP30SLC6A3PTPN1PTPN11HDAC1 | |
| SCHEMBL7231198 | 0.89 | SMN1; SMN2 (0.47) | USP30SLC6A3SLC6A4PTPN1PTPN11 | |
| SCHEMBL7234180 | 0.89 | USP30 (0.42) | USP30SLC6A3PTPN1PTPN11CNR1 | |
| SCHEMBL7226143 | 0.89 | PTPN11 (0.49) | USP30SLC6A3PTPN1PTPN11HDAC1 | |
| SCHEMBL7223371 | 0.89 | USP30 (0.42) | USP30SLC6A3PTPN1PTPN11HDAC1 | |
| SCHEMBL7071274 | 0.89 | USP30 (0.53) | USP30SLC6A3PTPN1HDAC1HDAC6 | |
| SCHEMBL7225875 | 0.89 | HDAC1 (0.46) | USP30PTPN1CNR1HDAC1HDAC3 | |
| SCHEMBL7223173 | 0.88 | CDC7 (0.43) | USP30SLC6A3PTPN1PTPN11CDC7 | |
| Hydrochloric Acid SCHEMBL7075524 | 0.88 | USP30 (0.52) | USP30SLC6A3PTPN1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |