Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.47 |
| ▸ | RAB9A | P51151 | 13/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345941 | 0.79 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2NOTUMPOLB | |
| SCHEMBL8631839 | 0.79 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL7301794 | 0.79 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL344372 | 0.79 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL209522 | 0.79 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL345944 | 0.79 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL3621627 | 0.79 | APP (0.50) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL2360245 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2HPGDNOTUM | |
| SCHEMBL352664 | 0.78 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL8626847 | 0.77 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2HPGDNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110846675-B | Synthetic method of 2- (5-aryl-1, 3, 4-oxadiazole-2-yl) aniline compound | 阜阳师范大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-110846675-A | Synthetic method of 2- (5-aryl-1, 3, 4-oxadiazole-2-yl) aniline compound | 阜阳师范大学 | 2020-02-28 | — | — | CN | disclosed |
| US-6605631-B1 | Controlling fungi and pests; improved activity and plant tolerability | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-12 | — | — | US | disclosed |
| EP-0668852-A1 | SUBSTITUTED ORTHO-ETHENYL-PHENYL ACETIC ACID DERIVATIVES | BASF Aktiengesellschaft (DE) | 1995-08-30 | — | — | EP | disclosed |