SCHEMBL7223302

SCHEMBL7223302

Clc1cc(Cl)cc(-n2cn[c]n2)c1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.38
TSHR P16473 1/20 0.35
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
ADRB1 P08588 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3240380 0.80 HSD17B10 (0.41) NOTUMTSHRCHRM1
SCHEMBL7222952 0.78 NOTUM (0.48) NOTUM
SCHEMBL796144 0.71 NOTUM (0.43) NOTUMTSHR
SCHEMBL7227830 0.68 NOTUM (0.44) NOTUMTSHR
SCHEMBL4042811 0.68 NOTUM (0.42) NOTUM
SCHEMBL2753518 0.65 NOTUM (0.42) NOTUMTSHRCHRM2CHRM4ADRB1
SCHEMBL2751028 0.65 NOTUM (0.38) NOTUMTSHRCHRM2CHRM4ADRB1
SCHEMBL7220247 0.63 HTR3E (0.41) TSHR
SCHEMBL16202027 0.63 KAT7 (0.40) NOTUM
SCHEMBL10360356 0.63 NOTUM (0.40) NOTUMTSHRCHRM2CHRM4ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6605631-B1 Controlling fungi and pests; improved activity and plant tolerability BASF AKTIENGESELLSCHAFT (DE) 2003-08-12 US disclosed