Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.56 |
| ▸ | MMP9 | P14780 | 19/20 | 0.56 |
| ▸ | MMP1 | P03956 | 5/20 | 0.53 |
| ▸ | MMP3 | P08254 | 4/20 | 0.53 |
| ▸ | MMP13 | P45452 | 4/20 | 0.53 |
| ▸ | MMP14 | P50281 | 4/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.45 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226591 | 0.88 | MMP2 (0.60) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7230600 | 0.86 | MMP2 (0.65) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7077886 | 0.81 | MMP2 (0.66) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7231569 | 0.79 | MMP2 (0.53) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7077896 | 0.75 | MMP2 (0.60) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7810615 | 0.72 | GAA (0.52) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL6719170 | 0.72 | MMP2 (0.61) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL18451265 | 0.71 | GAA (0.48) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL18562888 | 0.71 | GAA (0.48) | MMP2MMP9 | |
| SCHEMBL6578094 | 0.70 | MMP2 (0.65) | MMP2MMP9MMP1MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605604-B1 | Tumour necrosis factor alpha release inhibitors; efficiency treatment of cancers, rheumatic diseases, arthritis, ulcers, atherosclerosis, asthma | LES LABORATOIRES SERVIER (FR) | 2003-08-12 | — | — | US | disclosed |