Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | UGCG | Q16739 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229707 | 0.99 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTTDP1UGCGKDM4E | |
| Hydrochloric Acid SCHEMBL7228991 | 0.98 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTTDP1UGCGKDM4E | |
| SCHEMBL7223883 | 0.89 | PSMB1 (0.54) | UGCGPSMB1PSMB5LTA4HHRH3 | |
| SCHEMBL7223322 | 0.88 | PSMB1 (0.52) | UGCGPSMB1PSMB5LTA4HHRH3 | |
| Hydrochloric Acid SCHEMBL7223567 | 0.87 | PSMB1 (0.51) | TDP1UGCGPSMB1PSMB5LTA4H | |
| SCHEMBL7223901 | 0.83 | UGCG (0.39) | HTTUGCGDRD2DRD4SIGMAR1 | |
| SCHEMBL7229703 | 0.82 | UGCG (0.39) | HTTUGCGDRD2DRD4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7228986 | 0.81 | UGCG (0.39) | HTTUGCGDRD2DRD4SIGMAR1 | |
| SCHEMBL7223351 | 0.78 | TAS1R3 (0.44) | HTTUGCG | |
| SCHEMBL7222878 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTTDP1KDM4EPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | claimed |
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | disclosed |