SCHEMBL722408

SCHEMBL722408

C[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CC[C@](O)(C(=O)COP(=O)(O)O)[C@@]3(C)CC(=O)[C@@]12F

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.64
NR3C1 P04150 7/20 0.59
PGR P06401 2/20 0.59
HIF1A Q16665 2/20 0.59
HRH1 P35367 2/20 0.59
CYP2C19 P33261 1/20 0.56
FNTA P49354 4/20 0.53
FNTB P49356 4/20 0.53
ALDH1A1 P00352 2/20 0.49
MAPK1 P28482 1/20 0.49
AR P10275 3/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
BLM P54132 1/20 0.46
TSHR P16473 1/20 0.46
LMNA P02545 2/20 0.45
SERPINA6 P08185 1/20 0.45
CYP3A4 P08684 1/20 0.44
CHRM4 P08173 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4738 0.88 NR3C1 (0.76) SHBGNR3C1PGRHIF1AHRH1
SCHEMBL9389444 0.87 NR3C1 (0.78) SHBGNR3C1PGRHIF1AHRH1
SCHEMBL4546 0.86 NR3C1 (0.74) SHBGNR3C1PGRHIF1AHRH1
SCHEMBL143178 0.86 NR3C1 (0.74) SHBGNR3C1PGRHIF1AHRH1
SCHEMBL11037287 0.81 SHBG (0.72) SHBGNR3C1PGRHIF1AHRH1
SCHEMBL11042434 0.80 SHBG (0.56) SHBGNR3C1PGRHIF1AHRH1
SCHEMBL11123749 0.80 SHBG (0.56) SHBGNR3C1PGRHIF1AHRH1
SCHEMBL11039814 0.80 SHBG (0.56) SHBGNR3C1PGRHIF1AHRH1
SCHEMBL11040666 0.80 SHBG (0.56) SHBGNR3C1PGRHIF1AHRH1
SCHEMBL794298 0.76 FNTA (0.77) SHBGNR3C1PGRHIF1ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080038316-A1 Conveniently implantable sustained release drug compositions RAMSCOR, INC. 2008-02-14 US claimed
EP-3700595-B1 KITS FOR ANCHORING IMPLANTABLE MEDICAL DEVICES MEDTRONIC INC (US) 2024-06-19 EP disclosed
CN-117956956-A Surgical system and method of use 美敦力公司 2024-04-30 CN disclosed
US-11944825-B2 Surgical system and methods of use MEDTRONIC, INC (US) 2024-04-02 US disclosed
EP-3568168-B1 TUBE COVERING FOR AN IMPLANTABLE DEVICE MEDTRONIC INC (US) 2023-11-22 EP disclosed
EP-4274629-A1 SURGICAL SYSTEM AND METHODS OF USE Medtronic, Inc. (US) 2023-11-15 EP disclosed
EP-4274548-A1 SURGICAL SYSTEM AND METHODS OF USE Medtronic, Inc. (US) 2023-11-15 EP disclosed
CN-116583310-A Surgical system and method of use 美敦力公司 2023-08-11 CN disclosed
CN-116583312-A Surgical system and method of use 美敦力公司 2023-08-11 CN disclosed
US-20230173764-A1 SURGICAL SYSTEM AND METHODS OF USE MEDTRONIC INC. (US) 2023-06-08 US disclosed
US-20090018559-A1 Temporarily Stiffened Mesh Prostheses TYRX PHARMA, INC. (US) 2009-01-15 US disclosed
WO-2008136856-A2 RESORBABLE POUCHES FOR IMPLANTABLE MEDICAL DEVICES TYRX PHARMA, INC. (US) 2008-11-13 WO disclosed
WO-2008127411-A1 MESH POUCHES FOR IMPLANTABLE MEDICAL DEVICES TYRX PHARMA, INC. (US) 2008-10-23 WO disclosed
US-20080132922-A1 Mesh Pouches for Implantable Medical Devices TYRX PHARMA, INC. (US) 2008-06-05 US disclosed
US-20080128315-A1 Biodegradable polylactic acid polymer pouches for pacemaker, defibrillator, pulse generator cardiac rhythm mamagent devices; antimicrobial agents, anesthetics, anti-inflammatory agents, anti-scarring drugs in polymer matrix; barrier to microbial colonization of medical device during surgical implantation TYRX PHARMA, INC. (US) 2008-06-05 US disclosed
US-20080038316-A1 Conveniently implantable sustained release drug compositions RAMSCOR, INC. 2008-02-14 US disclosed
US-20070198040-A1 Temporarily Stiffened Mesh Prostheses TYRX PHARMA INC. (US) 2007-08-23 US disclosed
EP-1793803-A2 CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS Ramscor, Inc. (US) 2007-06-13 EP disclosed
WO-2006039336-A2 CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS RAMSCOR, INC. (US) 2006-04-13 WO disclosed
US-20060073182-A1 Conveniently implantable sustained release drug compositions RAMSCOR, INC. 2006-04-06 US disclosed