Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040631 | 0.67 | TAAR1 (0.54) | KDM4EMAPTALDH1A1NPC1ADORA1 | |
| SCHEMBL395611 | 0.66 | PTPRC (0.55) | KDM4EMAPTALDH1A1NPC1ADORA1 | |
| SCHEMBL31366955 | 0.66 | PTPRC (0.55) | KDM4EMAPTALDH1A1NPC1ADORA1 | |
| SCHEMBL6048484 | 0.66 | GABRA1 (0.49) | KDM4EMAPTALDH1A1NPC1LMNA | |
| Hydrochloric Acid SCHEMBL6048595 | 0.65 | GABRA1 (0.48) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL15020886 | 0.65 | MAP2K4 (0.49) | KDM4EMAPTALDH1A1NPC1GAA | |
| SCHEMBL9308665 | 0.65 | CD274 (0.52) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL5282347 | 0.63 | PTPRC (0.55) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL1500077 | 0.63 | KDR (0.57) | KDM4EMAPTALDH1A1NPC1GAA | |
| SCHEMBL6289617 | 0.62 | CYP1A2 (0.50) | KDM4EMAPTALDH1A1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573270-B1 | Endothelin receptor antagonists | PFIZER INC. | 2003-06-03 | — | — | US | disclosed |