Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27619772 | 0.78 | TRIM24 (0.47) | TRIM24TRIM33MAOBTSHRALDH1A1 | |
| SCHEMBL732708 | 0.69 | — | — | |
| SCHEMBL6316147 | 0.68 | MAOB (0.40) | TRIM24TRIM33MAOBTSHRALDH1A1 | |
| SCHEMBL17599975 | 0.67 | TRIM24 (0.40) | TRIM24TRIM33MAOBTSHRALDH1A1 | |
| SCHEMBL31530729 | 0.67 | MAOB (0.39) | TRIM24TRIM33MAOBTSHRALDH1A1 | |
| SCHEMBL18393842 | 0.67 | MAOB (0.36) | TRIM24TRIM33MAOBTSHRALDH1A1 | |
| SCHEMBL12469514 | 0.66 | MAOB (0.44) | TRIM24TRIM33MAOBTSHRALDH1A1 | |
| SCHEMBL4884620 | 0.66 | — | — | |
| SCHEMBL2325762 | 0.66 | — | — | |
| SCHEMBL26466710 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573267-B2 | Central nervous system disorders | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-06-03 | — | — | US | disclosed |
| US-20020019436-A1 | Useful aroyl aminoacyl pyrrole compounds | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-02-14 | — | — | US | disclosed |
| WO-2002002521-A2 | AROYL AMINOACYL PYRROLE COMPOUNDS AND THEIR PHARMACEUTICAL USE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019436-A1 | Useful aroyl aminoacyl pyrrole compounds | ABAT, GAP43, AADAT | TRIM24 1705/4885TRIM33 831/4885MAOB 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.