Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.88 |
| ▸ | APEX1 | P27695 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734714 | 0.87 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL17772674 | 0.85 | ALDH1A1 (0.82) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL11808900 | 0.83 | APEX1 (1.00) | ALDH1A1APEX1MEN1KMT2AKDM4E | |
| SCHEMBL5329443 | 0.82 | APEX1 (0.82) | ALDH1A1APEX1MEN1KMT2AKDM4E | |
| SCHEMBL11253338 | 0.82 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL11258740 | 0.81 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL10487900 | 0.79 | MEN1 (0.72) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL11263773 | 0.79 | MEN1 (0.72) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL5324208 | 0.78 | ALDH1A1 (0.67) | ALDH1A1APEX1MEN1KMT2ATSHR | |
| SCHEMBL11514777 | 0.78 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506738-B1 | Treatment of viral infections. More particularly, the invention provides benzimidazolone derivatives for the treatment of respiratory syncytial virus infection. | BRISTOL-MYERS SQUIBB COMPANY | 2003-01-14 | — | — | US | disclosed |
| WO-2002026228-A1 | BENZIMIDAZOLONE ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |